Curriculum Vitae: Celia Quevedo, Ph. D.

BSc in Biology, Complutense University (Madrid). She earned her Ph.D. in Biochemistry and Molecular Biology studying the regulation of protein initiation factors in neurons treated with the growth factor IGF-1 at the Hospital Ramon y Cajal (Madrid, Spain). Upon completing her Ph.D., she took a post-doctoral position in the Cancer Research Programme at the Hospital for Sick Children (Toronto, Canada), where she continued with the study of cell signaling pathways implicated in mammalian neuronal survival and growth. Besides this, she specialized in the genetic model C. elegans to study the roles of p53 and Akt in the DNA damage response. Her growing interest in cancer area made her joined the Cancer Center (Salamanca), where she familiarized with models of knockout mice for the guanine nucleotide exchange factor for Rho-family G -proteins Vav3.

She is currently a Project manager in Biobide, where she is in charge of the projects related with cancer.

MOST RELEVANT ARTICLES

• C. Quevedo, D.R. Kaplan and W.B. Derry. AKT-1 regulates DNA damage-induced germline apoptosis in C. elegans. Current Biology 17 (3) (2007), 286-292.
• D. C. Lin, C. Quevedo, N.E. Brewer, A. Bell, J. Testa, M.L.Grimes, F. D. Miller and D. R. Kaplan. APPL1 associates with TrkA and GIPC1, and is required for nerve growth factor-mediated signal transduction. Molecular and Cell Biology 23 (2006), 8928-8941.
• H.N. Marsh, *C.I. Dubreil, *C. Quevedo, A. Lee, M. Majdan, G. Walsh, S. Hausdorff, F.A. Said, O. Zoueva, M. Kozlowski, K. Siminovitch, B.G. Neel, F.D. Miller and D.R Kaplan. SHP-1 negatively regulates neuronal survival by functioning as a TrkA phosphatase. Journal of Cell Biology 163 (2003), Nº 5, 999-1010. *Equal contribution of both authors.
• C. Quevedo, M. Salinas and A. Alcázar. Initiation factor 2B activity is regulated by protein phosphatase 1, which is activated by de mitogen-activated protein kinase-dependent pathway in insulin-like growth factor 1-stimulated neuronal cells. The Journal of Biological Chemistry 278 (2003), Nº 19, 16579-16586.
• C. Quevedo, A. Alcázar and M. Salinas. Two different signal transduction pathways are implicated in the regulation of initiation factor 2B activity in insulin-like growth factor-1-stimulated neuronal cells. The Journal of Biological Chemistry 275 (2000), Nº 25, 19192-19197.